黎颀
Center for Plant Molecular Biology - ZMBP
University of Tübingen
Auf der Morgenstelle 32, D-72076 Tübingen, Germany
Phone: +49(0)7071-2978089
Email: qi.li@zmbp.uni-tuebingen.de
个人信息
Born June 16, 1993, Jiangxi, China
Nationality: People’s Republic of China
教育与工作经历
2010.9 - 2014.7 B.S. in Agronomy
College of Agronomy and Biotechnology
China Agricultural University, Beijing, China
2014.9 - 2020.9 Ph.D. in Genetics
Supervisor: Prof. Dr. Yongrui Wu
Dissertation Title: Maize Endosperm-Imprinted Gene Floury3 Regulates Seed Filling
Center for Excellence in Molecular Plant Sciences
Chinese Academy of Sciences, Shanghai, China
2020.9 - Now Postdoc in Developmental Biology
Advisor: Prof. Dr. Marja Timmermans
Department of Developmental Genetics
Center for Plant Molecular Biology - ZMBP
University of Tübingen, Tübingen, Germany
发表论文
Hailiang Zhao, Yao Qin, Ziyi Xiao, Qi Li, Ning Yang, Zhenyuan Pan, Dianming Gong, Qin Sun, Fang Yang, Zuxin Zhang, Yongrui Wu, Cao Xu and Fazhan Qiu. (2020). Loss of Function of an RNAPIII Subunit Leads to Impaired Maize Kernel Development. Plant Physiology, 184(1):359-373.
Qi Li, Yongrui Wu. (2020). The Encyclopedia of Maize Kernel Gene Expression. Journal of Integrative Plant Biology, 62(7):879-881.
Xixi Zheng#, Qi Li#, Changsheng Li, Dong An, Qiao Xiao, Wenqin Wang and Yongrui Wu. (2019). Intra-Kernel Reallocation of Proteins in Maize Depends on VP1-Mediated Scutellum Development and Nutrient Assimilation. The Plant Cell, 31(11):2613-2635.
Jiechen Wang#, Chen Ji#, Qi Li, Yong Zhou and Yongrui Wu. (2018). Genome-Wide Analysis of the Plant-Specific PLATZ Proteins in Maize and Identification of Their General Role in Interaction with RNA Polymerase III Complex. BMC Plant Biology, 18(1):221.
Qi Li#, Jiechen Wang#, Jianwei Ye#, Xixi Zheng, Xiaoli Xiang, Changsheng Li, Miaomiao Fu, Qiong Wang, Zhiyong Zhang and Yongrui Wu. (2017). The Maize Imprinted Gene Floury3 Encodes a PLATZ Protein Required for tRNA and 5S rRNA Transcription Through Interaction with RNA Polymerase III. The Plant Cell, 29(10):2661-2675.
# co-first authors
研究内容
Within the maize kernel, the endosperm takes up and stores nutrients from the mother plant, and additionally, serves to nourish the growing embryo via nutrient transfer into the scutellum (cotyledon). In my PhD research, I asked how nutrient reallocation from the mother plant to the endosperm and embryo is regulated.
We cloned the gene underlying the classical endosperm-filling defective mutant floury3, and showed this encodes a PLATZ transcription factor expressed specifically in starchy endosperm cells. We demonstrated that FL3 interacts with RNA polymerase III to regulate tRNA and 5S-rRNA accumulation, and hence, modulates starch and storage protein synthesis (Li, Wang, Ye, et al, 2017). We further showed that Fl3 is paternally imprinted under proximal and distant cis-regulation (unpublished), implying maternal control on nutrient allocation to the seed.
Additionally, we developed an RNAi-based system to alter intra-kernel nutrient reallocation, and showed that down-regulation of α-zeins, the predominant endosperm storage proteins, greatly enhanced the transport of nutrients into the embryo, resulting in an enlarged scutellum. These responses we showed are mediated by the embryo-specific transcription factor VIVIPAROUS1, which thus provides a key link coordinating endosperm nutritional status and embryo growth (Zheng, Li, et al, 2017).
My long-term goal is to establish an independent research career studying embryogenesis in the grasses. To this end, I started my postdoctoral research in the lab of Prof. Dr. Marja Timmermans at University of Tübingen to investigate the role of small RNA signals in the establishment of the shoot stem cell niche during maize embryonic development.
获奖荣誉
2021 Humboldt Research Fellowship, Alexander von Humboldt Foundation.
2018 First-Degree Prize and Best Popularity Prize of the Short Talk, Plant Science Graduate Student Academic Forum in Institute of Botany, Chinese Academy of Sciences (IB-CAS).
2017 National Scholarship for Doctoral Students, Chinese Ministry of Education
2016 Excellent Students Award, University of Chinese Academy of Sciences.
2016 Third-Degree Prize of the Poster Presentation, National Congress of Plant Biology in Wuhan, Hubei.
2014-2019 National Scholarship for Postgraduate Students, University of Chinese Academy of Sciences.
INVITED TALKS
2021 The 4th European Maize Meeting, Regensburg, Germany.
2018 Plant Science Graduate Student Academic Forum. Institute of Botany, Chinese Academy of Sciences (IB-CAS), Beijing, China.
2017 The 59th Annual Maize Genetics Conference. Union Station, St. Louis, Missouri, USA.